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Maximum dose of diazepam


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Diazepam

4.10.2018 | Allison Baldwin

Recommended dose is 0.5 to 1.0 mg/kg diazepam IV, up to a maximum dose of 20 mg, in dogs. This dose can be repeated to effect or twice within two hours. Constant rate intravenous infusions of diazepam have been advocated in human and veterinary patients. The recommended dose is 2-5 mg/hr in 5% dextrose in.

Benzodiazepines (diazepam, lorazepam, midazolam, and clonazepam) are potent, fast-acting anticonvulsants and therefore (particularly diazepam), are the preferred initial therapy in status epilepticus (SE).

Case report Diazepam in severe tetanus treatment

12.18.2018 | Allison Baldwin
Maximum dose of diazepam

Diazepam controls the spasms by blocking the polysynaptic reflexes, working peripherally, without depressing the cortical center and has no cardiovascular or endocrine effects. High dose diazepam had been used and proved to be a good muscle relaxant. Diazepam seems to work better with tetanus than pancuronium.

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In three cases of severe tetanus presented here, the first two were managed by diazepam and pancuronium bromide and the last case by high dose diazepam only. Diazepam controls the spasms by blocking the polysynaptic reflexes, working peripherally, without depressing the cortical center and has no cardiovascular or endocrine effects. High dose diazepam had been used and proved to be a good muscle relaxant. Most complications of severe tetanus became more manageable. Diazepam seems to work better with tetanus than pancuronium bromide, but both drugs need mechanical ventilation. In the first case, the dose of diazepam was up to 480 mg/day. By using high dose diazepam in severe tetanus, management of the clinical manifestations of autonomic nerve involvement and the weaning process become easier. The causes of death in tetanus are muscle spasms and spasm of the larynx, which are caused by blocking the release of inhibitory neurotransmitters in the spinal synapses, causing the uncontrolled spread of impulses. In cases where the dose exceeds 240 mg per day in a child, a ventilator should be on hand, and if the dose required is more than 480 mg per day, other drugs should be considered.

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Paramedic Medications (Pediatric dose) Flashcards Quizlet

10.16.2018 | Alexander Brickman
Maximum dose of diazepam

200-500 mg/kg of a 10%-25% solution slow IV push (see below). May be repeated as necessary. maximum concentration of 12.5% (vasculature extremely sensitive to high concentrations). Diazepam AKA Valium and others. Seizure activity: 0.2 mg/kg to 0.5 mg/kg slow IV q 2-5 minutes up to 5 mg maximum dose 10 mg/kg.

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Diazepam Adult Dosing

7.13.2018 | Andrew Babcock
Maximum dose of diazepam

Diazepam adult dosing. anxiety. [2-10 mg PO bid-qid]: Alt: 2-10 mg IM/IV q3-4h prn; Info: taper dose gradually to D/C if long-term use. sedation, preop. [10 mg IM x1]: Start: before surgery. sedation, procedural status epilepticus. [5-10 mg IV q5-10min prn]: Max: 30 mg/total dose. *confusional arousals. [5-10 mg PO qhs].