Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. The first such drug, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955, and made available in 1960 by.
Benzodiazepines are categorized as either short-, intermediate-, or long-acting. Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA A receptor, resulting in sedative, hypnotic ( sleep-inducing ), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties. High doses of many shorter-acting benzodiazepines may also cause anterograde amnesia and dissociation. Short- and intermediate-acting benzodiazepines are preferred for the treatment of insomnia; longer-acting benzodiazepines are recommended for the treatment of anxiety.
Benzodiazepines have qualities that can help to reduce anxiety and seizures, relax the muscles, and induce sleep. Short-term use of these medications is generally safe and effective. However, long-term use is controversial because of the potential for tolerance, dependence, and other adverse effects.
"What are the benefits and risks of benzodiazepines?." Medical News Today. Retrieved from /articles/262809.php. APA Nordqvist, J. (2017, October 25).
All references are available in the References tab. Article last updated by Adam Felman on Wed 25 October 2017. Visit our Neurology / Neuroscience category page for the latest news on this subject, or sign up to our newsletter to receive the latest updates on Neurology / Neuroscience.
2017. < /articles/262809.php>. Web. "What are the benefits and risks of benzodiazepines?." Medical News Today.
Benzodiazepines are a class of drugs prescribed in the US. They are man-made and are used for the treatment of anxiety, panic disorders, insomnia, PMS, and nervousness. These drugs are addictive if you take them for a long period of time or abuse them. Withdrawal symptoms can occur if you stop taking.
Sleep Quiz: Test Your Medical IQ.
Could you suffer a panic attack? Take this Panic Attacks Quiz to learn causes, symptoms, and treatments for panic disorder. Use.
Examples of oral benzodiazepines are: Formulations of benzodiazepines.
Adult men and women use benzodiazepines to treat:
home / sleep health center / sleep a-z list / benzodiazepines (benzodiazepine drug class) drug monograph.
Do you know the difference between seizures and epilepsy? What are the types of seizures? Take the Epilepsy & Seizures Quiz to.
Sedatives (for example, insomnia medicine) and other medicine that cause sedation, for example:
It is very difficult to recover from benzodiazepine addiction because these drugs change the chemistry of the brain.
A family of prescription tranquilizers, benzodiazepines are used for the treatment of sleeping and anxiety disorders. Benzos are addictive and often abused.
In order to boost their buzz, some users will mix the drugs with other central nervous system (CNS) depressants. Mixing benzodiazepines with other prescription and illicit drugs greatly increases the odds of fatal overdose. Alcohol is typically the chosen CNS sedative to combine with benzodiazepines, but users might also take benzos in conjunction with opiate drugs to escalate both highs.
Benzodiazepine overdose can slow breathing and heart rates until they stop compley, resulting in death.
The prevalence of benzodiazepines as popular, oft-prescribed anti-anxiety medications means that people from every demographic and lifestyle can be exposed to them.
Benzodiazepines. Profile. Benzodiazepines are among the most commonly prescribed depressant medications in the United States today. More than 15 different types of benzodiazepine medications exist to treat a wide array of both psychological and physical maladies based on dosage and implications.1.
Long Term Effects 11.
This neurotransmitter has an inhibitory effect on motor neurons, thus the presence of GABA slows or stops neuronal activity. Benzodiazepines enhance the activity of GABA, effectively slowing nerve impulses throughout the body. Benzodiazepines affect a key neurotransmitter in the brain called gamma-amino butyric acid (GABA). 7. The human nervous system has two different types of benzodiazepine receptors: one that causes the anti-anxiety effect, and one that elicits the sedative effect.